APC Anti-Mouse IL-10 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD22156F
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Overview

Circle
Product Name
APC Anti-Mouse IL-10 Antibody
Catalog Number
RD22156F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat

Background

Circle
L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.

Immunogen Information

Circle
Gene ID
16153
Swissprot
P18893
Synonyms
Interleukin-10IL-10Cytokine synthesis inhibitory factorCSIF

Applications

Circle
Reactivity
Mouse
Tested Applications
ICFCM
Conjugation
APC
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Research Areas

Circle

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