APLP1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD267484A
Western blot analysis of extracts of various cell lines using APLP1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human colon carcinoma using APLP1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse heart using APLP1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
APLP1 Polyclonal Antibody
Catalog Number
RD267484A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Immunogen Information
Immunogen
Recombinant fusion protein of human APLP1 (NP_005157.1).
Gene ID
333
Swissprot
P51693
Synonyms
APLP1APLP
Calculated MW
72 kDa
Observed MW
65-70 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas