APPL1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of A172 cell using APPL1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human esophagus cancer using APPL1 Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human lung cancer using APPL1 Polyclonal Antibody at dilution of 1:70
Product Name
APPL1 Polyclonal Antibody
Catalog Number
RD75083A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Immunogen Information
Immunogen
Recombinant protein of human APPL1
Swissprot
Q9UKG1
Synonyms
Adapter protein containing PH domainAdaptor Protein Containing pH DomainAdaptor protein containing pH domain PTB domain and leucine zipper motif 1Adaptor protein containing pH domain PTB domain and leucine zipper motifAdaptor protein phosphotyrosine i
Calculated MW
80 kDa
Gene Accession
BC028599
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.