The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
Immunogen Information
Immunogen
Synthetic peptide of human AQP2
Swissprot
P41181
Synonyms
ADH water channelAQP 2AQP CDAQP-2AQP-CDAQP2AQP2AQPCDAquaporin 2 collecting ductAquaporin CDAquaporin-2Aquaporin-CDAquaporin2Aquaporine 2Collecting duct water channel proteinMGC34501Water channel aquaporin 2Water channel protein for renal
Gene Accession
NP_000477
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4