Liver arginase(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).
Immunogen Information
Immunogen
Recombinant Human ARG1 protein expressed by E.coli
Swissprot
P05089
Synonyms
A IAlARG 1arg1ARGI1Arginase 1Arginase liverArginase type IArginaseliverArginase-1Arginase1Liver type arginaseLiver-type arginaseType I arginase
Calculated MW
48 kDa
Observed MW
48 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:200-1:500
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.