RHO GTPases regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15. GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.
Immunogen Information
Immunogen
Recombinant protein of human ARHGAP15
Swissprot
Q53QZ3
Synonyms
ArhGAP15BM046RHG15Rho GTPase activating protein 15Rho GTPase-activating protein 15Rho type GTPase activating protein 15Rho-type GTPase-activating protein 15
Calculated MW
55 kDa
Gene Accession
BC016701
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4