Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.
Immunogen Information
Immunogen
Synthetic peptide of human ARHGAP45
Swissprot
Q92619
Synonyms
HLA HA1hmha1HMHA1KIAA0223mHag HA-1Minor histocompatibility antigen HA 1Minor histocompatibility antigen HA-1Minor histocompatibility protein HA 1