ARHGDIB Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253461A
Western blot analysis of 293T A431 and HepG2 cell lysates using ARHGDIB Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ARHGDIB Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ARHGDIB Polyclonal Antibody at dilution of 1:35(×200)
Variation
Quantity
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Overview
Product Name
ARHGDIB Polyclonal Antibody
Catalog Number
RD253461A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them.
It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.
Immunogen Information
Immunogen
Synthetic peptide of human ARHGDIB
Swissprot
P52566
Synonyms
ArhgdibD4D4 GDP dissociation inhibitorGDIA 2GDIA2GDID 4GDID4GDIR2GDP dissociation inhibitor D4LY GDILy-GDILYGDIMGC108926RAP1GN1Rho GDI 2Rho GDI betaRho GDI2Rho GDP dissociation inhibitor (GDI) betaRho GDP dissociation inhibitor 2Rho GDP
Calculated MW
23 kDa
Observed MW
Refer to figures
Gene Accession
NP001166
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas