This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
Immunogen Information
Immunogen
Fusion protein of human ARPC1B
Swissprot
O15143
Synonyms
Actin related protein 2/3 complex subunit 1B 41kDaActin related protein 2/3 complex subunit 1BActin-related protein 2/3 complex subunit 1BARC1BARC41Arp2/3 complex 41 kDa subunitARP2/3 protein complex subunit p41Arpc1bp40 ARCp41 ARCp41-Arc