This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Immunogen
Recombinant protein of human ASB2
Swissprot
Q96Q27
Synonyms
Ankyrin repeat and SOCS box 2 containing proteinAnkyrin repeat and SOCS box containing 2Ankyrin repeat and SOCS box containing protein 2Ankyrin repeat and SOCS box containing protein 2aAnkyrin repeat and SOCS box protein 2Ankyrin repeat containing pr
Gene Accession
BC032354
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4