ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.
Immunogen Information
Immunogen
Recombinant protein of human ASB8
Swissprot
Q9H765
Synonyms
Ankyrin repeat and SOCS box containing 8Ankyrin repeat and SOCS box protein 8ASB 8ASB-8ASB8ASB8FLJ21255MGC5540OTTHUMP00000237000OTTHUMP00000237001OTTHUMP00000237007OTTHUMP00000237009OTTHUMP00000237010PP14212
Gene Accession
BC001321
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4