ASH2L Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87924A
Western blot analysis of extracts of various cell lines using ASH2L Polyclonal Antibody at 1:3000 dilution.
Product Name
ASH2L Polyclonal Antibody
Catalog Number
RD87924A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.
Immunogen Information
Immunogen
Recombinant fusion protein of human ASH2L
Gene ID
9070
Swissprot
Q9UBL3
Synonyms
ASH2LASH2ASH2L1ASH2L2Bre2
Calculated MW
61kDa/63kDa
Observed MW
61kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas