ASIC3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219330A
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ASIC3 Polyclonal Antibody at dilution of 1:40(×200)
Product Name
ASIC3 Polyclonal Antibody
Catalog Number
RD219330A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
Immunogen Information
Immunogen
Synthetic peptide of human ASIC3
Swissprot
Q9UHC3
Synonyms
ACCN 3Accn3ACCN3Acid sensing ion channel 3Acid-sensing ion channel 3Amiloride sensitive cation channel 3Amiloride sensitive cation channel 3 testisAmiloride-sensitive cation channel 3ASIC 3ASIC3DRASIChASIC 3hASIC3hTNaC 1hTNaC1Modulatory sub
Gene Accession
NP004760
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:2000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas