ASNA1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253162A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ASNA1 Polyclonal Antibody at dilution of 1:70(×200)
Product Name
ASNA1 Polyclonal Antibody
Catalog Number
RD253162A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.
Immunogen Information
Immunogen
Fusion protein of human ASNA1
Swissprot
O43681
Synonyms
ARSA 1ARSAArsA arsenite transporter ATP binding homolog 1ArsA arsenite transporterATP bindingE. colihomolog of1ArsA arsenite transporterATP-bindinghomolog 1 (bacterial)ARSA IARSA-IARSA1ARSAIArsenical pump driving ATPaseArsenical pump-drivi
Gene Accession
BC002651
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.26 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas