ASXL1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD90036A
Western blot analysis of extracts of Mouse liver using ASXL1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of Mouse liver using ASXL1 Polyclonal Antibody at 1:1000 dilution.
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Overview

Circle
Product Name
ASXL1 Polyclonal Antibody
Catalog Number
RD90036A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human ASXL1
Gene ID
171023
Swissprot
Q8IXJ9
Synonyms
ASXL1BOPSMDS
Calculated MW
26kDa/41kDa
Observed MW
41kDa

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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