Ataxin 3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80919A
Immunofluorescence analysis of HeLa cells using Ataxin 3 Polyclonal Antibody
Confocal immunofluorescence analysis of U-2 OS cells using Ataxin 3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
Ataxin 3 Polyclonal Antibody
Catalog Number
RD80919A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human Ataxin 3 (NP_004984.2).
Gene ID
4287
Swissprot
P54252
Synonyms
ATXN3AT3ATX3JOSMJDMJD1SCA3ataxin-3Ataxin 3
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas