This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ATF2
Swissprot
P15336,P16951,Q00969
Synonyms
Activating transcription factor 2Activating transcription factor 2 splice variant ATF2 var2ATF 2Atf-2Atf2ATF2 proteinATF2cAMP Response Element Binding Protein 2cAMP response element binding protein CRE BP1cAMP response element-binding protein CRE
Calculated MW
52 kDa
Observed MW
52 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4