Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
Synthetic peptide of human APG4B
Swissprot
Q9Y4P1
Synonyms
APG4 autophagy 4 homolog BAPG4BATG4 autophagy related 4 homolog B (S. cerevisiae)ATG4BATG4BAUT like 1 cysteine endopeptidaseAUT-like 1 cysteine endopeptidaseAUTL1Autophagin 1Autophagin-1Autophagy related 4B cysteine peptidaseAutophagy related c
Calculated MW
43 kDa
Gene Accession
NP_037457
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4