ATG5 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70489A
Immunohistochemistry analysis of paraffin-embedded human liver cancer using ATG5 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using ATG5 Polyclonal Antibody at dilution of 1:400.
Product Name
ATG5 Polyclonal Antibody
Catalog Number
RD70489A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
ATG5,also named as APG5L and ASP,belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process,possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process,occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to mouse ATG5
Swissprot
Q9H1Y0,Q99J83
Synonyms
APG 5APG 5LAPG5APG5 autophagy 5 likeAPG5 likeAPG5-likeAPG5LApoptosis specific proteinApoptosis-specific proteinASPATG 5Atg5ATG5 autophagy related 5 homologATG5Autophagy protein 5Autophagy related 5hAPG5Homolog of S Cerevisiae autophagy 5
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.