ATG7 (Autophagy Related 7) is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Innate Immune System. GO annotations related to this gene include protein homodimerization activity and ubiquitin activating enzyme activity. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to mouse ATG7
Swissprot
O95352,Q9D906
Synonyms
1810013K23RikApg 7APG7 autophagy 7 likeAPG7 autophagy 7-like (S. cerevisiae)APG7 likeAPG7S. cerevisiaehomolog ofAPG7-likeAPG7LATG 7ATG12-activating enzyme E1 ATG7ATG7ATG7 autophagy related 7 homolog (S. cerevisiae)ATG7 autophagy related 7 ho
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4