Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.ATP5I (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit E) is a Protein Coding gene. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and purine nucleotides de novo biosynthesis. GO annotations related to this gene include ATPase activity and hydrogen ion transmembrane transporter activity.
Immunogen Information
Immunogen
Synthetic peptide of human ATP5I
Swissprot
P56385
Synonyms
ATP 5IATP 5KATP synthase e chain mitochondrialATP synthase H+ transporting mitochondrial F0 complex subunit EATP synthase subunit eATP synthase subunit e mitochondrialATP5IATP5IATP5KATPase subunit eF1F0 ATP synthase murine e subunitMGC12532mit