This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Fusion protein of human ATRIP
Swissprot
Q8WXE1
Synonyms
AGS1ATIPATM and Rad3 related interacting proteinATM and Rad3-related-interacting proteinATR interacting proteinATR-interacting proteinAtripATRIPDKFZp762J2115FLJ12343MGC20625MGC21482MGC26740