ATXN3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218525A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ATXN3 Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ATXN3 Polyclonal Antibody at dilution of 1:100(×200)
Product Name
ATXN3 Polyclonal Antibody
Catalog Number
RD218525A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Fusion protein of human ATXN3
Swissprot
P54252
Synonyms
AT3Ataxin 3ataxin 3 variant hataxin 3 variant mataxin 3 variant refAtaxin-3ATX3ATX3ATXN3EC 3.4.22.JOSJosephinMachado Joseph disease (spinocerebellar ataxia 3olivopontocerebellar ataxia 3autosomal dominantataxin 3)Machado Joseph diseaseMac
Gene Accession
BC033711
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas