The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human BAAT
Swissprot
Q14032
Synonyms
FLJ20300BAATBAATBACATBATBile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)Bile acid CoA:amino acid N acyltransferaseBile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferaseBile acid Coenzyme A: amino a
Calculated MW
46 kDa
Gene Accession
BC009567
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4