The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Bad
Swissprot
Q92934,Q61337,O35147
Synonyms
AI325008BADBADBBC 2BBC2BBC6Bcl 2 Antagonist of Cell DeathBcl 2 Binding Component 6BCL X / BCL 2 Binding ProteinBCL X Binding ProteinBcl XL/Bcl 2 Associated Death PromoterBcl-2-binding component 6Bcl-2-like protein 8Bcl-XL/Bcl-2-associated dea
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:300
Concentration
300 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4