BAD Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD77253A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using BAD Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using BAD Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BAD Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BAD Polyclonal Antibody at dilution 1:60
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Overview

Circle
Product Name
BAD Polyclonal Antibody
Catalog Number
RD77253A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Immunogen Information

Circle
Immunogen
Recombinant protein of human BAD
Swissprot
Q92934
Synonyms
AI325008BADBADBBC 2BBC2BBC6Bcl 2 Antagonist of Cell DeathBcl 2 Binding Component 6BCL X / BCL 2 Binding ProteinBCL X Binding ProteinBcl XL/Bcl 2 Associated Death PromoterBcl-2-binding component 6Bcl-2-like protein 8Bcl-XL/Bcl-2-associated dea
Gene Accession
BC001901

Applications

Circle
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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