The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Immunogen Information
Immunogen
Recombinant protein of human BAD
Swissprot
Q92934
Synonyms
AI325008BADBADBBC 2BBC2BBC6Bcl 2 Antagonist of Cell DeathBcl 2 Binding Component 6BCL X / BCL 2 Binding ProteinBCL X Binding ProteinBcl XL/Bcl 2 Associated Death PromoterBcl-2-binding component 6Bcl-2-like protein 8Bcl-XL/Bcl-2-associated dea
Gene Accession
BC001901
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4