BAG3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86698A
Western blot with BAG3 Polyclonal antibody at dilution of 1:2000.lane 1:Hela whole cell lysate, lane 2:K562 whole cell lysate,lane 3:A431 whole cell lysate,lane 4：Rat heart
Product Name
BAG3 Polyclonal Antibody
Catalog Number
RD86698A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.
Immunogen Information
Immunogen
Recombinant Human BAG3 protein expressed by E.coli
Swissprot
O95817
Synonyms
BAG family molecular chaperone regulator 3BAG-3Bcl-2-associated athanogene 3Bcl-2-binding protein BisBIS
Calculated MW
12 kDa
Observed MW
14 kDa
Applications
Reactivity
Human,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
0.4mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas