BAK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75038A
Western Blot analysis of Hela, A431, 293T and Jurkat cell using BAK1 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human esophagus cancer using BAK1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human breast cancer using BAK1 Polyclonal Antibody at dilution of 1:50
Product Name
BAK1 Polyclonal Antibody
Catalog Number
RD75038A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Immunogen Information
Immunogen
Recombinant protein of human BAK1
Swissprot
Q16611
Synonyms
Apoptosis regulator BAKBAKBAK likeBak NTBAKBak1Bcl 2 homologous antagonist/killerBcl 2 like 7 proteinBcl-2 homologous antagonist/killerBcl-2-like protein 7BCL2 antagonist/killer 1Bcl2 like 7 ProteinBcl2-L-7BCL2L7CDN1Cell death inhibitor 1M
Calculated MW
23 kDa
Gene Accession
BC004431
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas