BAX Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85549A
Western Blot analysis of 1) Hela, 2) C2C12, 3) PC-12 cells using Bax Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using Bax Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Mouse kidney tissue using Bax Monoclonal Antibody at dilution of 1:200.
Product Name
BAX Monoclonal Antibody
Catalog Number
RD85549A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Immunogen Information
Immunogen
Synthetic Peptide of Bax
Swissprot
Q07812
Synonyms
Apoptosis regulator BAXBAXBax-proteinBAXBAXABaxdelta2G9Baxdelta2G9omegaBaxdelta2omegaBcl-2-like protein 4BCL2 associated X proteinBCL2 associated X protein omegaBCL2 associated X protein transcript variant delta2Bcl2-L-4BCL2L4membrane isofor
Observed MW
20 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p
Conjugation
Unconjugated
Dilution
WB 1:1000-2000, IHC 1:100-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas