Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Immunogen Information
Immunogen
Synthetic Peptide of Bax
Swissprot
Q07812
Synonyms
Apoptosis regulator BAXBAXBax-proteinBAXBAXABaxdelta2G9Baxdelta2G9omegaBaxdelta2omegaBcl-2-like protein 4BCL2 associated X proteinBCL2 associated X protein omegaBCL2 associated X protein transcript variant delta2Bcl2-L-4BCL2L4membrane isofor
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:100-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4