BAX Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90740A
Western blot with BAX Polyclonal antibody at dilution of 1:1000.lane 1:MCF-7 whole cell lysate,lane 2:A549 whole cell lysate,lane 3:HepG2 whole cell lysate,lane 4:SH-SY5Y whole cell lysate,lane 5:C2C12 whole cell lysate,lane 6:NIH-3T3 whole cell lysate,lane 7:Raw264.7 whole cell lysate,lane 8:C6 whole cell lysate
Product Name
BAX Polyclonal Antibody
Catalog Number
RD90740A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2,and functions as an apoptotic activator. This protein is reported to interact with,and increase the opening of,the mitochondrial voltage-dependent anion channel (VDAC),which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants,which encode different isoforms,have been reported for this gene.
Immunogen Information
Immunogen
Recombinant Human BAX Protein expressed by E.coli
Swissprot
Q07812
Synonyms
Apoptosis regulator BAXBcl-2-like protein 4 (Bcl2-L-4)BAXBCL2L4
Calculated MW
19kDa
Observed MW
15kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas