This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16.
Immunogen Information
Immunogen
Recombinant protein of human BCAP31
Swissprot
P51572
Synonyms
6C6 AG6C6 AG tumor associated antigen6C6-AG tumor-associated antigen6C6AG6C6AG tumor associated antigenAccessory protein BAP 31Accessory protein BAP31B cell receptor associated protein 31B-cell receptor-associated protein 31BA31BAP 31Bap31BAP3
Calculated MW
28 kDa
Gene Accession
BC014323
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4