BCL10 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77887A
Western Blot analysis of HepG2, Raji and 293T cell using BCL10 Polyclonal Antibody at dilution of 1:950
Immunohistochemistry of paraffin-embedded Human thyroid cancer using BCL10 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human gastric cancer using BCL10 Polyclonal Antibody at dilution of 1:40
Product Name
BCL10 Polyclonal Antibody
Catalog Number
RD77887A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma.
Immunogen Information
Immunogen
Recombinant protein of human BCL10
Swissprot
O95999
Synonyms
AI132454B cell CLL/lymphoma 10B cell lymphoma/leukemia10B-cell CLL/lymphoma 10B-cell leukemia/lymphoma 10B-cell lymphoma/leukemia 10Bcl 10Bcl-10Bcl10BCL10c E10c-E10C81403CARD containing apoptotic signaling proteinCARD containing molecule enh
Calculated MW
26 kDa
Gene Accession
BC053617
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas