BCL2 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85462A
Western Blot analysis of Hela cells using BCL2 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human tonsil tissue using BCL2 Monoclonal Antibody at dilution of 1:200.
Product Name
BCL2 Monoclonal Antibody
Catalog Number
RD85462A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P10415
Synonyms
Apoptosis regulator Bcl 2Apoptosis regulator Bcl-2Apoptosis regulator Bcl2AW986256B cell CLL/lymphoma 2B cell leukemia/lymphoma 2Bcl-2Bcl2BCL2C430015F12RikD630044D05RikD830018M01RikLeukemia/lymphomaB-cell2Oncogene B-cell leukemia 2PPP1R50
Calculated MW
26 kDa
Observed MW
26 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p
Conjugation
Unconjugated
Dilution
WB 1:1000-2000, IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas