BCL2A1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87101A
Immunofluorescence analysis of Jurkat cells using BCL2A1 Polyclonal Antibody at dilution of 1:250 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Jurkat cells using BCL2A1 Polyclonal Antibody at dilution of 1:250 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of THP-1 cells using BCL2A1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of THP-1 cells using BCL2A1 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
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Overview

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Product Name
BCL2A1 Polyclonal Antibody
Catalog Number
RD87101A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

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Immunogen
A synthetic peptide of human BCL2A1
Gene ID
597
Swissprot
Q16548
Synonyms
BCL2A1ACC-1ACC-2ACC1ACC2BCL2L5BFL1GRSHBPA1
Calculated MW
33kDa/46kDa
Observed MW
50kDa

Applications

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Reactivity
Human
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Research Areas

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