Human peripheral blood lymphocytes are stained with FITC Anti-Human CD19 Antibody and Biotin Anti-Human CD40 Antibody followed by Streptavidin-AF 647 (Left). Lymphocytes are stained with FITC Anti-Human CD19 Antibody and Biotin Mouse IgG1, κ Isotype Control followed by Streptavidin-AF 647 (Right).
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).
Immunogen Information
Gene ID
958
Synonyms
Bp50CDw40CD40L receptorTNFRSF5
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
Biotin
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.