Biotin Anti-Mouse CD161/NK1.1 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
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Overview

Circle
Product Name
Biotin Anti-Mouse CD161/NK1.1 Antibody
Catalog Number
RD20026F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse

Background

Circle
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Immunogen Information

Circle
Gene ID
17059
Swissprot
P27814,P27812,Q99JB4
Synonyms
Killer cell lectin-like receptor subfamily B member 1CKlrb1cCD161 antigen-like family member CLy-55cCD161/NK1.1NKR-P1.9NKR-P1CNKR-P1 40CD161c

Applications

Circle
Reactivity
Mouse
Tested Applications
FCM
Conjugation
Biotin
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C. Do not freeze.

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