BMP2 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70548A
Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 Monoclonal Antibody at dilution of 1:400.
Product Name
BMP2 Monoclonal Antibody
Catalog Number
RD70548A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Mouse
Background
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse BMP2
Swissprot
P12643,P21274,P49001
Synonyms
BDA2BMP-2BMP-2ABmp2BMP2BMP2ABone morphogenetic protein 2Bone morphogenetic protein 2A
Applications
Reactivity
Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
2.65 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas