BMP2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79990A
Western blot analysis of extracts of various cell lines using BMP2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human colon using BMP2 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse lung using BMP2 Polyclonal Antibody at dilution of 1:200 (40x lens).
Product Name
BMP2 Polyclonal Antibody
Catalog Number
RD79990A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Immunogen Information
Immunogen
Recombinant fusion protein of human BMP2 (NP_001191.1).
Gene ID
650
Swissprot
P12643
Synonyms
BDA2BMP2ABMP2
Calculated MW
44 kDa
Observed MW
45 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas