BMP2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of various samples using BMP2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse bone marrow using BMP2 Polyclonal Antibody at dilution of 1:300.
Product Name
BMP2 Polyclonal Antibody
Catalog Number
RD70320A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse BMP2
Swissprot
P12643,P21274,P49001
Synonyms
BDA2BMP-2BMP-2ABmp2BMP2BMP2ABone morphogenetic protein 2Bone morphogenetic protein 2A
Calculated MW
45 kDa
Observed MW
45 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:200-1:800
Concentration
2.4 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas