This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, whicHuman, Mouseediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen Information
Immunogen
Recombinant protein of human BMX
Swissprot
P51813
Synonyms
BmxBMX non receptor tyrosine kinaseBMXBONE MARROW KINASEX-LINKEDBone marrow tyrosine kinase gene in chromosome X proteinCytoplasmic tyrosine protein kinase BMXCytoplasmic tyrosine-protein kinase BMXEpithelial and endothelial tyrosine kinaseETKNK
Gene Accession
BC016652
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4