The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif whicHuman, Mouseay be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Immunogen Information
Immunogen
Synthetic peptide of human BRD4
Swissprot
O60885
Synonyms
Brd4BRD4-NUT FUSIONBRD4-NUT fusion oncoproteinBRD4Bromodomain containing 4bromodomain containing protein 4Bromodomain-containing protein 4CAPchromosome associated proteinHUNK1HUNKIMCAPMitotic chromosome-associated proteinProtein HUNK1
Calculated MW
152 kDa
Gene Accession
NP_490597
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4