BRI3BP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253455A
Western blot analysis of RAW264.7 and K562 cell lysates using BRI3BP Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using BRI3BP Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using BRI3BP Polyclonal Antibody at dilution of 1:35(×200)
Variation
Quantity
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Overview
Product Name
BRI3BP Polyclonal Antibody
Catalog Number
RD253455A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.
Immunogen Information
Immunogen
Synthetic peptide of human BRI3BP
Swissprot
Q8WY22
Synonyms
BNAS1BRI3 binding proteinBRI3-binding proteinBRI3BBri3bpCervical cancer 1 proto oncogene binding protein KG19Cervical cancer 1 proto-oncogene-binding protein KG19cervical cancer oncogene binding proteinHCCR-2HCCR1HCCRBP-1I3 binding proteinI3-b
Calculated MW
28 kDa
Observed MW
Refer to figures
Gene Accession
NP542193
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas