BYSL Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunohistochemistry of paraffin-embedded Rat ovary using BYSL Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat ovary using BYSL Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human colon carcinoma using BYSL Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human colon carcinoma using BYSL Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast cancer using BYSL Polyclonal Antibody at dilution of  1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast cancer using BYSL Polyclonal Antibody at dilution of 1:100 (40x lens).
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Overview

Circle
Product Name
BYSL Polyclonal Antibody
Catalog Number
RD265860A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human BYSL (NP_004044.3).
Gene ID
705
Swissprot
Q13895
Synonyms
BYSLBYSTINbystin

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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