The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse c-FOS
Swissprot
P01100,P01101,P12841
Synonyms
Activator protein 1AP 1C FOSCellular oncogene c fosCellular oncogene fosFBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS)FBJ murine osteosarcoma viral oncogene homologFBJ murine osteosarcoma viral v fos oncogene homologFBJ Oste
Calculated MW
62 kDa
Observed MW
62 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:500-1:2000, IF 1:200-1:1000
Concentration
0.97 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4