C15orf23 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70080A
Western Blot analysis of A431 cell using C15orf23 Polyclonal Antibody at dilution of 1:500
Product Name
C15orf23 Polyclonal Antibody
Catalog Number
RD70080A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
Immunogen Information
Immunogen
Recombinant Human Small kinetochore-associated protein protein
Swissprot
Q9Y448
Synonyms
KNSTRNC15orf23chromosome 15 open reading frame 23HSD11KinastrinKinetochore-localized astrin-binding proteinKinetochore-localized astrin/SPAG5-binding proteinPutative TRAF4-associated factor 1SKAPsmall kinetochore associated proteinT4AF1TRAF4 as
Calculated MW
35 kDa
Observed MW
35 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas