C5AR1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218573A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using C5AR1 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using C5AR1 Polyclonal Antibody at dilution of 1:50(×200)
Product Name
C5AR1 Polyclonal Antibody
Catalog Number
RD218573A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Immunogen Information
Immunogen
Fusion protein of human C5AR1
Swissprot
P21730
Synonyms
ANAPHYLATOXIN RECEPTORC5a anaphylatoxin chemotactic receptorC5a anaphylatoxin receptorC5AC5a ligandC5a-RC5aRC5ARc5ar1C5R1CD88CD88 antigenComplement component 5 receptor 1Complement component 5 receptor 2Complement component 5a receptor 1
Gene Accession
BC008982
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas