C9orf116 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218760A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using C9orf116 Polyclonal Antibody at dilution of 1:55(×200)
Product Name
C9orf116 Polyclonal Antibody
Catalog Number
RD218760A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.
Immunogen Information
Immunogen
Fusion protein of human C9orf116
Swissprot
Q5BN46
Synonyms
C9orf116CI116Pierce 1UPF0691 protein C9orf116
Gene Accession
BC021261
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas