This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Immunogen Information
Immunogen
Recombinant protein of human CANX
Swissprot
P27824
Synonyms
CalnexinCALXCANXCNXFLJ26570Histocompatibility complex class I antigen binding protein p88IP90Major histocompatibility complex class I antigen-binding protein p88p90
Calculated MW
68 kDa
Gene Accession
BC003552
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4