The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human CAPN1
Swissprot
P07384
Synonyms
Ca2 activated neutral proteaseCalcium activated neutral proteinaseCalcium activated neutral proteinase small subunitCalcium dependent protease small subunit 1Calcium dependent protease small subunitCalcium-activated neutral proteinase 1Calpain 1Cal
Calculated MW
82 kDa
Gene Accession
BC017200
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4